⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5351721 | 0.88 | — | — | |
| SCHEMBL2050243 | 0.84 | — | — | |
| SCHEMBL7599169 | 0.77 | GPR3 (0.40) | — | |
| SCHEMBL5352026 | 0.76 | — | — | |
| SCHEMBL1050872 | 0.76 | — | — | |
| SCHEMBL8853041 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL60641 | 0.73 | PDCD1 (0.31) | — | |
| SCHEMBL5359556 | 0.72 | GSTP1 (0.35) | — | |
| SCHEMBL1049600 | 0.72 | — | — | |
| SCHEMBL390616 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964679-B2 | 1-Butene polymer polymerization catalyst system: a Hf, Ti or Zr metallocene having an indene ring and a fluorene ring bridged by a silane group; an alumoxane or a compound that forms an alkyl metallocene cation; and an organoaluminum compound; (2,4,6-trimethylindenyl)(9-fluorenyl)dimethylsilane | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-21 | — | — | US | disclosed |
| US-20080269439-A1 | Process for the Polymerization of Alpha Olefins | BASELL POLYOLEFINE GMBH (DE) | 2008-10-30 | — | — | US | disclosed |
| EP-1877453-A1 | PROCESS FOR THE POLYMERIZATION OF ALPHA OLEFINS | Basell Polyolefine GmbH (DE) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006117285-A1 | PROCESS FOR THE POLYMERIZATION OF ALPHA OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2006-11-09 | — | — | WO | disclosed |