SCHEMBL2046452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2046756	0.91	HTR1A (0.34)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2045785	0.89	MEN1 (0.40)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL4444473	0.89	POLB (0.36)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2046017	0.89	HTR1A (0.34)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2049642	0.89	HTR1A (0.36)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2046336	0.89	HTR1A (0.34)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2047163	0.89	RORC (0.34)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2045011	0.89	ESR1 (0.34)	ALDH1A1HPGDHTR1ASLC6A2SLC6A4
	SCHEMBL4441314	0.89	KDM4E (0.36)	KDM4EALDH1A1HPGDHSD17B10HTR1A
	SCHEMBL2045992	0.89	ACHE (0.39)	KDM4EHTR1ASLC6A2SLC6A4RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.