Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988862 | 0.84 | MAPT (0.56) | SLC2A1RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL14988861 | 0.84 | MAPT (0.56) | SLC2A1RAB9AKMT2ANPC1MEN1 | |
| SCHEMBL6214564 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1RAB9AKMT2ANPC1 | |
| SCHEMBL2828903 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1RAB9AKMT2ANPC1 | |
| Potassium Ion SCHEMBL9750508 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1RAB9AKMT2ANPC1 | |
| SCHEMBL9750505 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1RAB9AKMT2ANPC1 | |
| SCHEMBL9750506 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1RAB9AKMT2ANPC1 | |
| SCHEMBL28404135 | 0.79 | POLB (0.52) | SLC2A1PTGS2RAB9AKMT2ANPC1 | |
| SCHEMBL28404138 | 0.79 | POLB (0.52) | SLC2A1PTGS2RAB9AKMT2ANPC1 | |
| SCHEMBL9380814 | 0.78 | NPC1 (0.54) | SLC2A1PTGS2PTGS1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | SLC2A1 696/4885PTGS2 1327/4885PTGS1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.