Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28404138 | 1.00 | POLB (0.52) | POLBKMT2AMEN1MAPTPTGS2 | |
| SCHEMBL14659792 | 0.86 | POLB (0.68) | POLBKMT2AMEN1MAPTPTGS2 | |
| SCHEMBL12973292 | 0.86 | POLB (0.68) | POLBKMT2AMEN1MAPTPTGS2 | |
| SCHEMBL20464764 | 0.79 | SLC2A1 (0.56) | KMT2AMEN1MAPTPTGS2MAPK1 | |
| SCHEMBL20493592 | 0.78 | KMT2A (0.50) | POLBKMT2AMEN1MAPTPTGS2 | |
| SCHEMBL14659297 | 0.77 | MAOB (0.76) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL14659295 | 0.77 | MAOB (0.76) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL306161 | 0.77 | POLB (0.81) | POLBKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL28404931 | 0.76 | SLC2A1 (0.56) | KMT2AMEN1MAPTALDH1A1SLC2A1 | |
| SCHEMBL28404929 | 0.76 | SLC2A1 (0.56) | KMT2AMEN1MAPTALDH1A1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105524053-B | Tetrahydrobenzothiophene compounds | 广东东阳光药业有限公司 | 2020-06-05 | — | — | CN | disclosed |