Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.66 |
| ▸ | CLK2 | P49760 | 18/20 | 0.66 |
| ▸ | CLK3 | P49761 | 17/20 | 0.66 |
| ▸ | WNT1 | P04628 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465658 | 0.90 | CLK3 (0.65) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20465700 | 0.90 | CLK2 (0.60) | DYRK1ACLK2CLK3 | |
| SCHEMBL20465677 | 0.89 | CLK2 (0.73) | DYRK1ACLK2CLK3 | |
| SCHEMBL20465696 | 0.89 | DYRK1A (0.58) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20469538 | 0.89 | CLK2 (0.52) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20455107 | 0.88 | DYRK1A (0.66) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20465669 | 0.88 | CLK2 (0.62) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL18444462 | 0.88 | DYRK1A (0.74) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20455450 | 0.88 | CLK2 (0.64) | DYRK1ACLK2CLK3WNT1 | |
| SCHEMBL20437280 | 0.87 | WNT1 (0.59) | DYRK1ACLK2CLK3WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221350-A1 | 3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | VICKERS VENTURE FUND VI (PLAN) PTE. LTD. (SG) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221350-A1 | 3-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-1H-INDAZOLES AND THERAPEUTIC USES THEREOF | WNT1, WNT3, WNT3A | DYRK1A 545/4885CLK2 788/4885CLK3 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.