⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465788 | 1.00 | — | — | |
| SCHEMBL20465791 | 1.00 | — | — | |
| SCHEMBL20465787 | 0.78 | TDP1 (0.31) | — | |
| SCHEMBL20465792 | 0.78 | TDP1 (0.31) | — | |
| SCHEMBL20465789 | 0.78 | TDP1 (0.31) | — | |
| SCHEMBL11229667 | 0.75 | LMNA (0.41) | — | |
| SCHEMBL26881049 | 0.75 | — | — | |
| SCHEMBL23849709 | 0.72 | SLC6A2 (0.33) | — | |
| SCHEMBL23849717 | 0.72 | SLC6A2 (0.33) | — | |
| SCHEMBL20465785 | 0.70 | MAPK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024499-B2 | Muscarinic agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-07-02 | — | — | US | disclosed |
| US-12024499-B2 | Muscarinic agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2024-07-02 | — | — | US | disclosed |
| US-20230002354-A1 | MUSCARINIC AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2023-01-05 | — | — | US | disclosed |
| US-10738029-B2 | Muscarinic agonists | HEPTARES THERAPEUTICS LIMITED (GB) | 2020-08-11 | — | — | US | disclosed |
| US-20180222885-A1 | MUSCARINIC AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2018-08-09 | — | — | US | disclosed |
| US-20180222885-A1 | MUSCARINIC AGONISTS | NXERA PHARMA UK LIMITED (GB) | 2018-08-09 | — | — | US | disclosed |