Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.76 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20465846 | 1.00 | HTR7 (0.76) | HTR7DRD2TMEM97DRD4DRD3 | |
| SCHEMBL22219753 | 0.87 | HTR7 (0.73) | HTR7DRD2TMEM97 | |
| SCHEMBL22219778 | 0.87 | HTR7 (0.73) | HTR7DRD2TMEM97 | |
| SCHEMBL17592848 | 0.86 | HTR7 (1.00) | HTR7DRD2 | |
| SCHEMBL19458796 | 0.86 | HTR7 (1.00) | HTR7DRD2 | |
| SCHEMBL17592912 | 0.86 | HTR7 (1.00) | HTR7DRD2 | |
| SCHEMBL17592517 | 0.83 | HTR7 (1.00) | HTR7TMEM97 | |
| SCHEMBL19458801 | 0.83 | HTR7 (1.00) | HTR7TMEM97 | |
| SCHEMBL17593029 | 0.83 | HTR7 (1.00) | HTR7TMEM97 | |
| Trifluoroacetic Acid SCHEMBL18227620 | 0.79 | HTR7 (0.84) | HTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180221365-A1 | NOVEL SIGMA-2 RECEPTOR BINDERS AND THEIR METHOD OF USE | Temple University--of the Commonwealth System of Higher Education | 2018-08-09 | — | — | US | disclosed |
| US-20180221365-A1 | NOVEL SIGMA-2 RECEPTOR BINDERS AND THEIR METHOD OF USE | Temple University--of the Commonwealth System of Higher Education | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221365-A1 | NOVEL SIGMA-2 RECEPTOR BINDERS AND THEIR METHOD OF USE | SIGMAR1, TMEM97, OPRL1 | HTR7 83/4885DRD2 209/4885TMEM97 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.