Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407811 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18484548 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL28269475 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL27801778 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL16699608 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| Benzyl Dimethylcarbamate SCHEMBL14031385 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDKMT2AMAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDKMT2AMAPK1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDKMT2AMAPK1 | |
| SCHEMBL18440474 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18484541 | 0.72 | SIGMAR1 (0.41) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10617675-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-04-14 | — | — | US | disclosed |
| US-20180221342-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10617675-B2 | Hepatitis C virus inhibitors | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 3966/4885CHRM2 4882/4885CHRM4 4859/4885 |
| US-20180221342-A1 | HEPATITIS C VIRUS INHIBITORS | HAVCR2, MAVS, EIF2AK2 | ALDH1A1 3966/4885CHRM2 4882/4885CHRM4 4859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.