Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.38 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18509898 | 0.92 | ELANE (0.43) | GPR174MAPTKDM4EMAPK1KMT2A | |
| SCHEMBL9607785 | 0.87 | ELANE (0.47) | MAPTKDM4EKMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL20469262 | 0.85 | KDM4E (0.36) | GPR174MAPTKDM4EKMT2ANPC1 | |
| SCHEMBL22600500 | 0.85 | GAA (0.39) | MAPTKMT2AMEN1NPC1TP53 | |
| SCHEMBL18522596 | 0.85 | KMT2A (0.38) | GPR174MAPTKDM4EMAPK1KMT2A | |
| SCHEMBL20469142 | 0.85 | FFAR1 (0.35) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL18869481 | 0.84 | BACE1 (0.49) | MAPTKDM4EKMT2AMEN1TP53 | |
| SCHEMBL19674709 | 0.84 | ELANE (0.40) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL21884911 | 0.83 | PTGER2 (0.36) | MAPTKDM4EMAPK1KMT2AMEN1 | |
| SCHEMBL18437003 | 0.83 | FFAR4 (0.35) | MAPTKDM4EMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351771-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-07-16 | — | — | US | disclosed |