SCHEMBL20469933

SCHEMBL20469933

COC1OC(CO)[C@H](O)[C@H](O)[C@@H]1NC(C)=O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.67
▸ THRB P10828 1/20 0.67
▸ MAPK1 P28482 2/20 0.64
▸ CA2 P00918 2/20 0.56
▸ CA9 Q16790 2/20 0.56
▸ CD69 Q07108 1/20 0.56
▸ CA1 P00915 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ POLB P06746 1/20 0.54
▸ LGALS3 P17931 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24916742 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL22606183 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL22596723 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL23705217 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL23705274 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL24223153 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL24943853 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL24916806 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL21415435 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9
SCHEMBL14899261 1.00 ALDH1A1 (0.67) ALDH1A1THRBMAPK1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263897-A1 CONJUGATE OF GALNAC AND SAPONIN, THERAPEUTIC COMPOSITION COMPRISING SAID CONJUGATE AND A GALNAC-OLIGONUCLEOTIDE CONJUGATE SAPREME TECHNOLOGIES B.V. (NL) 2023-08-24 — — US disclosed
US-20180221494-A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263897-A1 CONJUGATE OF GALNAC AND SAPONIN, THERAPEUTIC COMPOSITION COMPRISING SAID CONJUGATE AND A GALNAC-OLIGONUCLEOTIDE CONJUGATE ASGR1, GYS2, HCCS ALDH1A1 3111/4885THRB 1246/4885MAPK1 4249/4885
US-20180221494-A1 SITE-SPECIFIC DELIVERY OF NUCLEIC ACIDS BY COMBINING TARGETING LIGANDS WITH ENDOSOMOLYTIC COMPONENTS HAVCR2, LNPEP, BST2 ALDH1A1 4541/4885THRB 2461/4885MAPK1 4706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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