Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 8/20 | 0.50 |
| ▸ | GSTM2 | P28161 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20466174 | 0.83 | GSTP1 (0.58) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL3501548 | 0.77 | MEN1 (0.60) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL3500091 | 0.75 | MEN1 (0.60) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL22871986 | 0.73 | GSTP1 (0.57) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL7052057 | 0.72 | GSTM2 (0.66) | GSTP1GSTM2MEN1KMT2AALDH1A1 | |
| SCHEMBL10089701 | 0.70 | GSTM2 (0.56) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL3501565 | 0.69 | GSTP1 (0.52) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL1108120 | 0.69 | GSTP1 (0.63) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL18896943 | 0.69 | IDO1 (0.63) | GSTP1GSTM2MEN1KMT2ANPC1 | |
| SCHEMBL18895765 | 0.69 | IDO1 (0.56) | GSTP1GSTM2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815247-B2 | Functionalized NANOLUC inhibitors | PROMEGA CORPORATION (US) | 2020-10-27 | — | — | US | disclosed |
| US-20180222916-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815247-B2 | Functionalized NANOLUC inhibitors | RNGTT, LUC7L2, GUSB | GSTP1 27/4885GSTM2 295/4885MEN1 3584/4885 |
| US-20180222916-A1 | FUNCTIONALIZED NANOLUC INHIBITORS | RNGTT, LUC7L2, GUSB | GSTP1 27/4885GSTM2 295/4885MEN1 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.