Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | GSTP1 | P09211 | 8/20 | 0.54 |
| ▸ | GSTM2 | P28161 | 8/20 | 0.54 |
| ▸ | IDO1 | P14902 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.48 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.48 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.48 |
| ▸ | MYC | P01106 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500091 | 0.85 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL3501565 | 0.85 | GSTP1 (0.52) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL32687089 | 0.83 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL7052057 | 0.82 | GSTM2 (0.66) | MEN1KMT2AGSTP1GSTM2IDO1 | |
| SCHEMBL5708748 | 0.81 | MAPT (0.44) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL6849943 | 0.81 | TXNRD1 (0.46) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL20466174 | 0.81 | GSTP1 (0.58) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL10089701 | 0.80 | GSTM2 (0.56) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL31320344 | 0.79 | GSTP1 (0.57) | MEN1KMT2ANPC1RAB9AGSTP1 | |
| SCHEMBL18896943 | 0.78 | IDO1 (0.63) | MEN1KMT2ANPC1RAB9AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | claimed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | claimed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | claimed |
| EP-1328244-B1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AG (DE) | 2006-10-11 | — | — | EP | claimed |
| US-6773463-B2 | A MIXTURE OF A 4-NITRO-2,1,3-BENZOXADIAZOLE, A 4-NITRO-2,1,3-BENZOTHIADIAZOLE, OR A 4-NITRO-2,1,3-BENZO-SELENADIAZOLE AND AT LEAST ONE AMINE, PHENOL, OR AMINONITROBENZENE; INTENSE COLORATIONS; MILD CONDITIONS; DIRECT HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | claimed |
| US-6749645-B2 | RED AND BLUE DIRECT DYE; HAIR | WELLA AKTIENGESELLSCHAFT (DE) | 2004-06-15 | — | — | US | claimed |
| EP-1328244-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-07-23 | — | — | EP | claimed |
| EP-1317242-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | Wella Aktiengesellschaft (DE) | 2003-06-11 | — | — | EP | claimed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | claimed |
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-12-19 | — | — | US | claimed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| WO-2002022094-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | claimed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | disclosed |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-04-17 | — | — | US | disclosed |
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2002-12-19 | — | — | US | disclosed |
| WO-2002022093-A1 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
| WO-2002022094-A1 | USE OF 4-NITRO-2,1,3-BENZOXADIAZOL DERIVATIVES AS DYES IN COLOURING AGENTS FOR KERATIN FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189032-A1 | Use of 4-nitro-2,1,3,-benzoxadiazole derivatives as dyes in colouring agents for keratin fibres | CBR1, CYC1, CBR3 | MEN1 4392/4885KMT2A 2588/4885NPC1 3590/4885 |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | GSTO1, GSTP1, GSR | MEN1 4463/4885KMT2A 1267/4885NPC1 3081/4885 |
| US-20030070239-A1 | Agent and method for dyeing keratin fibers | KRT18, AOC1, S100B | MEN1 2811/4885KMT2A 686/4885NPC1 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.