Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11264529 | 0.71 | TP53 (0.52) | TP53EGFRERBB2LMNAL3MBTL1 | |
| SCHEMBL11145953 | 0.67 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14217912 | 0.67 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL23373396 | 0.66 | TP53 (0.45) | TP53L3MBTL1KMT2ALTB4RLTB4R2 | |
| SCHEMBL21078085 | 0.65 | TP53 (0.47) | TP53EGFRLMNAL3MBTL1MEN1 | |
| SCHEMBL18835129 | 0.65 | TP53 (0.47) | TP53L3MBTL1MEN1KMT2AESR1 | |
| SCHEMBL15382025 | 0.64 | KMT2A (0.50) | EGFRFAAHPHGDHMGLLCA12 | |
| SCHEMBL6909714 | 0.64 | FAAH (0.47) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL13649116 | 0.64 | TP53 (0.46) | TP53SIGMAR1 | |
| SCHEMBL24426151 | 0.64 | TP53 (0.39) | TP53FAAHPHGDHMGLLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018142334-A1 | FORMULATIONS COMPRISING OXALATE SALTS OF TENELIGLIPTIN AND SOLVATES THEREOF | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2018-08-09 | — | — | WO | disclosed |