Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4816453 | 0.85 | P2RY6 (0.36) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL28575356 | 0.78 | TYMP (0.48) | TYMP | |
| SCHEMBL27574601 | 0.77 | KDM4E (0.44) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL27744847 | 0.72 | LMNA (0.46) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL28483586 | 0.71 | LMNA (0.44) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL27538958 | 0.69 | LMNA (0.52) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL28687653 | 0.69 | LMNA (0.49) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL6294148 | 0.68 | ENPP1 (0.46) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL27831324 | 0.68 | LMNA (0.45) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL3436939 | 0.68 | TYMP (0.45) | POLBTYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002835-A1 | GENETIC TOOL FOR THE TRANSFORMATION OF CLOSTRIDIUM BACTERIA | STICHTING WAGENINGEN RESEARCH (NL) | 2024-01-04 | — | — | US | disclosed |
| US-11746346-B2 | Genetic tool for the transformation of Clostridium bacteria | STICHTING WAGENINGEN RESEARCH (NL) | 2023-09-05 | — | — | US | disclosed |
| WO-2021260322-A1 | STRAINS OF CLOSTRIDIUM BACTERIA RESISTANT TO 5-FLUOROURACIL, GENETIC TOOLS AND USES THEREOF | IFP Energies Nouvelles (FR) | 2021-12-30 | — | — | WO | disclosed |
| CN-113853430-A | Non-viral modification of mesenchymal stem cells | 新加坡国立大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112029698-A | Engineering bacterium for degrading organophosphorus pesticide and construction method thereof | 南开大学 | 2020-12-04 | — | — | CN | disclosed |
| US-20180305680-A1 | GENETIC TOOL FOR THE TRANSFORMATION OF CLOSTRIDIUM BACTERIA | STICHTING WAGENINGEN RESEARCH (NL) | 2018-10-25 | — | — | US | disclosed |
| EP-3362559-A1 | GENETIC TOOL FOR THE TRANSFORMATION OFCLOSTRIDIUM | IFP Energies nouvelles (FR) | 2018-08-22 | — | — | EP | disclosed |