Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.40 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786418 | 0.81 | UPP1 (0.57) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL13650209 | 0.78 | LMNA (0.50) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL11099078 | 0.78 | LMNA (0.51) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL3863318 | 0.77 | KDM4E (0.44) | ENPP1KDM4ECYP1A2GRIA1GRIA2 | |
| SCHEMBL5017332 | 0.76 | LMNA (0.49) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL11399957 | 0.74 | SMN1; SMN2 (0.52) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL10479252 | 0.74 | LMNA (0.44) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL6372044 | 0.74 | LMNA (0.56) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL11397970 | 0.73 | SMN1; SMN2 (0.51) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL10479219 | 0.72 | LMNA (0.42) | KDM4ECYP1A2GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6896871-B2 | Biphosphonate conjugates and methods of making and using the same | MBC RESEARCH, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20020142994-A1 | Bisphosphonate conjugates and methods of making and using the same | MBC PHARMA, INC. | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142994-A1 | Bisphosphonate conjugates and methods of making and using the same | SOST, BPGM, PTH1R | ENPP1 26/4885KDM4E 3027/4885CYP1A2 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.