Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.59 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.59 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.59 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.59 |
| ▸ | CBFB | Q13951 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967325 | 0.86 | KDM4E (0.62) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL12948580 | 0.80 | NPC1 (0.66) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL1043657 | 0.80 | HPGDS (0.52) | KDM4EHPGDSALOX15HTTPSMD14 | |
| SCHEMBL17221411 | 0.80 | MAOB (0.53) | MAPTKDM4ENPC1RAB9AHPGDS | |
| SCHEMBL975217 | 0.79 | KDM4E (0.60) | MAPTKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3589284 | 0.79 | MGLL (0.49) | MAPTNPC1RAB9AHPGDSSMN1; SMN2 | |
| SCHEMBL3575601 | 0.78 | HPGDS (0.54) | MAPTRAB9AHPGDSSMN1; SMN2ALOX15 | |
| SCHEMBL19021550 | 0.78 | HPGDS (0.74) | HPGDS | |
| SCHEMBL2001821 | 0.78 | HPGDS (0.51) | HPGDSALOX15HTTPSMD14 | |
| SCHEMBL20741514 | 0.78 | KDM4E (0.64) | MAPTKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
| US-20180237448-A1 | NOVEL QUINOLINE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180237448-A1 | NOVEL QUINOLINE DERIVATIVES AND PREPARATION THEREOF | ABL1, FLT3, MAP3K7 | MAPT 2812/4885KDM4E 892/4885MEN1 1506/4885 |
| US-10227355-B2 | Quinoline derivatives and preparation thereof | ABL1, FLT3, MAP3K7 | MAPT 2415/4885KDM4E 939/4885MEN1 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.