Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | NQO2 | P16083 | 5/20 | 0.63 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612603 | 1.00 | MAPT (0.67) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL20272058 | 0.84 | ACHE (0.69) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL31011404 | 0.82 | ALDH1A1 (0.71) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL3244933 | 0.82 | ALDH1A1 (0.71) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL3728001 | 0.82 | ALDH1A1 (0.71) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL17483584 | 0.82 | NQO2 (0.68) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL17483582 | 0.82 | NQO2 (0.68) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL345562 | 0.81 | ALDH1A1 (1.00) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL20475366 | 0.79 | NQO2 (0.72) | MAPTKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL20475263 | 0.79 | ACHE (0.62) | MAPTKMT2ARAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2018152436-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) | 2018-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | ROS1, NOX4, PRDX3 | MAPT 2601/4885KMT2A 3688/4885RAB9A 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.