Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31173630 | 1.00 | MAPT (0.60) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL29745032 | 0.85 | GAA (0.73) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL76547 | 0.85 | GAA (0.73) | MAPTKDM4EGAAPTK2BMAPK1 | |
| Ammonia Solution, Strong SCHEMBL14746306 | 0.84 | GAA (0.71) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL24838802 | 0.83 | HDAC3 (0.54) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL25894824 | 0.82 | MAPT (0.88) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL16053964 | 0.81 | LGMN (0.62) | MAPTKDM4EMAPK1HTTKMT2A | |
| SCHEMBL28845811 | 0.80 | ADRA2C (0.70) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL3935104 | 0.79 | MAPT (0.65) | MAPTKDM4EGAAPTK2BMAPK1 | |
| SCHEMBL30565926 | 0.79 | MAPT (0.65) | MAPTKDM4EGAAPTK2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018151810-A1 | DEFINING RNA-SMALL MOLECULE AFFINITY LANDSCAPES ENABLES DESIGN OF A SMALL MOLECULAR INHIBITOR OF AN ONCOGENIC NON-CODING RNA | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-08-23 | — | — | WO | disclosed |