Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 10/20 | 0.44 |
| ▸ | ME1 | P48163 | 10/20 | 0.44 |
| ▸ | ME3 | Q16798 | 10/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521781 | 1.00 | ME2 (0.44) | ME2ME1ME3GPR119DDB1 | |
| SCHEMBL29522264 | 0.87 | AKR1C3 (0.44) | GPR119DDB1CRBNCKS1BSKP1 | |
| SCHEMBL15206161 | 0.87 | AKR1C3 (0.44) | GPR119DDB1CRBNCKS1BSKP1 | |
| SCHEMBL29890806 | 0.81 | GPR119 (0.60) | ME2ME1ME3GPR119DDB1 | |
| SCHEMBL13279435 | 0.81 | GPR119 (0.60) | ME2ME1ME3GPR119DDB1 | |
| SCHEMBL20475492 | 0.81 | ME2 (0.49) | ME2ME1ME3ESR2 | |
| SCHEMBL20475502 | 0.80 | USP30 (0.49) | GPR119DDB1CRBNCKS1BSKP1 | |
| SCHEMBL20956331 | 0.77 | TRPV1 (0.42) | GPR119CKS1BSKP1SKP2MAP4K4 | |
| SCHEMBL15908706 | 0.75 | GPR119 (0.53) | GPR119CKS1BSKP1SKP2HDAC1 | |
| SCHEMBL20475504 | 0.74 | GPR119 (0.41) | GPR119DDB1CRBNCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369095-B | Aminopyrimidine compounds useful as SSAO inhibitors and methods for preparing the same | 伊莱利利公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114369095-A | Aminopyrimidine compounds useful as SSAO inhibitors and methods of making the same | 伊莱利利公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-108778278-B | Aminopyrimidine compounds useful as SSAO inhibitors | 伊莱利利公司 | 2022-01-28 | — | — | CN | disclosed |
| EP-3582780-B1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | LILLY CO ELI (US) | 2021-10-13 | — | — | EP | disclosed |
| US-10471060-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | ELI LILLY AND COMPANY (US) | 2019-11-12 | — | — | US | disclosed |
| US-20190275041-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2019-09-12 | — | — | US | disclosed |
| US-10278970-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | ELI LILLY AND COMPANY (US) | 2019-05-07 | — | — | US | disclosed |
| US-20180296560-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | ELI LILLY AND COMPANY | 2018-10-18 | — | — | US | disclosed |
| WO-2018151985-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | ELI LILLY AND COMPANY (US) | 2018-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10278970-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | DPYD, TYMP, NUDT1 | ME2 1907/4885ME1 2147/4885ME3 1683/4885 |
| US-20180296560-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | DPYD, TYMP, NUDT1 | ME2 1907/4885ME1 2147/4885ME3 1683/4885 |
| US-10471060-B2 | Amino pyrimidine compounds useful as SSAO inhibitors | DPYD, TYMP, NUDT1 | ME2 1907/4885ME1 2147/4885ME3 1683/4885 |
| US-20190275041-A1 | AMINO PYRIMIDINE COMPOUNDS USEFUL AS SSAO INHIBITORS | DPYD, TYMP, NUDT1 | ME2 1907/4885ME1 2147/4885ME3 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.