Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154319 | 0.84 | ALDH1A1 (0.41) | TDP1ALDH1A1TSHRCA2F2 | |
| SCHEMBL19589026 | 0.80 | CA2 (0.42) | TDP1ALDH1A1TSHRCA2F2 | |
| SCHEMBL12163595 | 0.78 | ALDH1A1 (0.46) | TDP1ALDH1A1TSHRCA2GRIN2D | |
| SCHEMBL1002129 | 0.78 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRCA2KMT2A | |
| SCHEMBL958496 | 0.78 | LMNA (0.50) | TDP1ALDH1A1F2F10F12 | |
| SCHEMBL29712527 | 0.78 | LMNA (0.50) | TDP1ALDH1A1F2F10F12 | |
| Hydrochloric Acid SCHEMBL3065338 | 0.77 | LMNA (0.48) | TDP1ALDH1A1F2F10F12 | |
| Hydrochloric Acid SCHEMBL31138645 | 0.77 | LMNA (0.48) | TDP1ALDH1A1F2F10F12 | |
| Hydrochloric Acid SCHEMBL20576674 | 0.77 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRCA2KMT2A | |
| Bromide SCHEMBL6851251 | 0.77 | ALDH1A1 (0.48) | TDP1ALDH1A1TSHRCA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018149419-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2018-08-23 | — | — | WO | disclosed |