Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20477489 | 1.00 | FAAH (0.36) | FAAHCHRNB2CHRNA7CHRNA4NOS1 | |
| SCHEMBL20477496 | 0.98 | FAAH (0.35) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL3305780 | 0.75 | FAAH (0.44) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL7541798 | 0.74 | NOS1 (0.44) | NOS1NOS2 | |
| SCHEMBL21859013 | 0.70 | FAAH (0.40) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL21859005 | 0.70 | FAAH (0.40) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL31558663 | 0.70 | FAAH (0.40) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL23672278 | 0.69 | FAAH (0.39) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL21859010 | 0.69 | FAAH (0.39) | FAAHCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL5013295 | 0.68 | FAAH (0.41) | FAAHCHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086982-B1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-08-29 | — | — | EP | disclosed |