⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304203 | 0.85 | TDP1 (0.54) | — | |
| SCHEMBL8074473 | 0.80 | ALDH1A1 (0.58) | — | |
| SCHEMBL19484390 | 0.79 | TDP1 (0.45) | — | |
| SCHEMBL129034 | 0.79 | TSHR (0.59) | — | |
| SCHEMBL29619673 | 0.78 | — | — | |
| SCHEMBL5821155 | 0.78 | — | — | |
| SCHEMBL33457 | 0.78 | — | — | |
| SCHEMBL9836081 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL6131221 | 0.78 | TDP1 (0.48) | — | |
| SCHEMBL19560102 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084913-A | Synthesis and refining method of monochloroganciclovir condensate | 上药康丽（常州）药业有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-110590591-B | Preparation method of iodixanol and iohexol impurities | 浙江海洲制药有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-109485567-B | Clean preparation method of 4-hydroxymethylthiazole and intermediate thereof | 上海博璞诺科技发展有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-110590591-A | Preparation method of iodixanol and iohexol impurities | 浙江海洲制药有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-109485567-A | A kind of clean method for preparing and its intermediate of 4- hydroxymethylthiazole | 上海博璞诺科技发展有限公司 | 2019-03-19 | — | — | CN | claimed |
| US-4395561-A | Synthesis of 3-hydroxyoxetane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1983-07-26 | — | — | US | claimed |
| CN-118084913-A | Synthesis and refining method of monochloroganciclovir condensate | 上药康丽（常州）药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084913-A | Synthesis and refining method of monochloroganciclovir condensate | 上药康丽（常州）药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| US-11993553-B2 | Preparation of cationic surfactants | SAUDI ARABIAN OIL COMPANY (SA) | 2024-05-28 | — | — | US | disclosed |
| US-11591291-B2 | Preparation of cationic surfactants | SAUDI ARABIAN OIL COMPANY (SA) | 2023-02-28 | — | — | US | disclosed |
| US-11591292-B2 | Preparation of cationic surfactants | SAUDI ARABIAN OIL COMPANY (SA) | 2023-02-28 | — | — | US | disclosed |
| CN-110590591-B | Preparation method of iodixanol and iohexol impurities | 浙江海洲制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-110590591-B | Preparation method of iodixanol and iohexol impurities | 浙江海洲制药有限公司 | 2022-05-17 | — | — | CN | disclosed |
| EP-0431838-A1 | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1991-06-12 | — | — | EP | disclosed |
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0400686-A1 | 2-Amino-9-[1,3bis-(isopropoxy)-propyl-2-oxymethyl]-purine, its utilization and medicaments containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0217207-A1 | 2-Amino purines substituted in positions 6 and 9, their use, medicaments containing these purines and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |
| US-4492794-A | 2-Guanidino-4-hydroxymethylthiazole and derivatives thereof | SHIONOGI & CO., LTD. (JP) | 1985-01-08 | — | — | US | disclosed |
| EP-0123741-A1 | 2-Guanidino-4-hydroxymethylthiazole and derivatives thereof | SHIONOGI & CO., LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |
| US-4395561-A | Synthesis of 3-hydroxyoxetane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1983-07-26 | — | — | US | disclosed |