SCHEMBL6131221

SCHEMBL6131221

CC(=O)OCC(O)COCC(O)COC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 5/20 0.43
USP2 O75604 4/20 0.43
MAPT P10636 4/20 0.43
CYP3A4 P08684 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HPGD P15428 1/20 0.43
MEN1 O00255 1/20 0.43
TP53 P04637 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
LMNA P02545 4/20 0.42
HSD17B10 Q99714 1/20 0.42
TSHR P16473 1/20 0.39
KDM4E B2RXH2 3/20 0.38
RECQL P46063 1/20 0.37
POLB P06746 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PGR P06401 1/20 0.34
CHRM2 P08172 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304203 0.92 TDP1 (0.54) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL15096923 0.89 ALDH1A1 (0.50) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL17480802 0.88 TDP1 (0.48) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL14528315 0.87 HSD17B10 (0.50) TDP1ALDH1A1USP2MAPTCYP3A4
Hydroquinone SCHEMBL6353777 0.86 ADRB2 (0.46) TDP1ALDH1A1USP2MAPTCYP3A4
Tromethamine SCHEMBL7036899 0.84 TDP1 (0.38) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL17482276 0.83 PRKCA (0.49) TDP1MEN1KMT2ALMNAKDM4E
SCHEMBL23818606 0.83 TDP1 (0.47) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL13176451 0.83 TDP1 (0.47) TDP1ALDH1A1USP2MAPTCYP3A4
SCHEMBL10020242 0.83 TDP1 (0.47) TDP1ALDH1A1USP2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030149219-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom BORIACK CLINTON J (US) 2003-08-07 US claimed
US-6534621-B2 Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative DOW GLOBAL TECHNOLOGIES INC. 2003-03-18 US claimed
EP-1290058-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-12 EP claimed
US-20020045707-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2002-04-18 US claimed
WO-2001088013-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2001-11-22 WO claimed
US-12638775-B2 Methods and compositions for improved patterning of photoresist TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) 2026-05-26 US disclosed
US-20250224673-A1 PHOTORESIST AND METHOD OF FORMATION AND USE TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2025-07-10 US disclosed
US-12287575-B2 Photoresist and method of formation and use TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2025-04-29 US disclosed
US-20240393685-A1 SEMICONDUCTOR DEVICE AND METHODS OF MANUFACTURE TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2024-11-28 US disclosed
US-20240387193-A1 SEMICONDUCTOR DEVICES WITH EXTERNAL CONNECTORS TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2024-11-21 US disclosed
US-20240371640-A1 UNDERLAYER OF MULTILAYER STRUCTURE AND METHODS OF USE THEREOF TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2024-11-07 US disclosed
CN-111863601-B Method for manufacturing semiconductor device and photoresist 台湾积体电路制造股份有限公司 2024-08-27 CN disclosed
US-20050165201-A1 Epoxidizing an alpha-halohydrin intermediate from a halide substitution-deesterification of an alpha -hydroxy ester derivative obtained by the coupling reaction of a phenol and a glycidyl ester BORIACK CLINTON J (US) 2005-07-28 US disclosed
US-6881529-B2 Positive photoresist transfer material and method for processing surface of substrate using the transfer material FUJI PHOTO FILM CO., LTD. (JP) 2005-04-19 US disclosed
US-20030149219-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom BORIACK CLINTON J (US) 2003-08-07 US disclosed
US-20030087179-A1 Positive photoresist transfer material and method for processing surface of substrate using the transfer material FUJI PHOTO FILM CO., LTD. 2003-05-08 US disclosed
US-6534621-B2 Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative DOW GLOBAL TECHNOLOGIES INC. 2003-03-18 US disclosed
EP-1290058-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2003-03-12 EP disclosed
US-20020045707-A1 Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom DOW GLOBAL TECHNOLOGIES INC. 2002-04-18 US disclosed
WO-2001088013-A2 PROCESS FOR MANUFACTURING A HYDROXYESTER DERIVATIVE INTERMEDIATE AND EPOXY RESINS PREPARED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2001-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12638775-B2 Methods and compositions for improved patterning of photoresist DSG1, SCO2, ERCC1 TDP1 295/4885ALDH1A1 1401/4885USP2 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.