Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | USP2 | O75604 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12863645 | 0.91 | ALDH1A1 (0.51) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL15693929 | 0.90 | USP2 (0.50) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL304203 | 0.89 | TDP1 (0.54) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL28563534 | 0.87 | MAPT (0.49) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL16322323 | 0.87 | MAPT (0.49) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL14599372 | 0.84 | USP2 (0.46) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL13625424 | 0.83 | TDP1 (0.46) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL6131221 | 0.82 | TDP1 (0.48) | ALDH1A1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL33457 | 0.82 | — | — | |
| SCHEMBL5821155 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579370-B1 | An optically active 1,5-disubstituted-2,4-0-isoproylidene-2,4-dihydroxypentane and a process for producing the same | CHISSO CORP (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0909757-A2 | Process for producing optically active pentanetetraols | CHISSO CORPORATION (JP) | 1999-04-21 | — | — | EP | disclosed |
| US-5449793-A | Process for producing an optically active 1,5-disubstituted-2,4-O-isopropylidene-2,4-dihydroxypentane | CHISSO CORPORATION (JP) | 1995-09-12 | — | — | US | disclosed |
| US-5329018-A | Optically active 1-5-disubstituted-2,4-o-isopropylidene-2,4-dihydroxypentane and a process for producing the same | CHISSO CORPORATION (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0579370-A2 | An optically active 1,5-disubstituted-2,4-0-isoproylidene-2,4-dihydroxypentane and a process for producing the same | CHISSO CORPORATION (JP) | 1994-01-19 | — | — | EP | disclosed |