Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL400786 | 0.85 | GPR35 (0.52) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17448374 | 0.83 | HDAC3 (0.49) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL2241077 | 0.82 | TSHR (0.52) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL6812309 | 0.80 | PTPN2 (0.49) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17081033 | 0.79 | TSHR (0.47) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL10144299 | 0.77 | GAA (0.50) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL6739730 | 0.77 | PTPN2 (0.46) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL422589 | 0.77 | POLB (0.57) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17447083 | 0.76 | GAA (0.49) | PTPN2HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL13961924 | 0.75 | GPR35 (0.48) | PTPN2HDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503655-B | Heterocyclic compound and organic electronic device using same | 机光科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |
| US-20180247770-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTRONIC DEVICE AND USING THE SAME | LUMINESCENCE TECHNOLOGY CORPORATION (TW) | 2018-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180247770-A1 | HETEROCYCLIC COMPOUND FOR ORGANIC ELECTRONIC DEVICE AND USING THE SAME | OR10J3, BMI1, SIK1 | PTPN2 3407/4885HDAC3 1638/4885HDAC4 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.