Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448374 | 0.95 | HDAC3 (0.49) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL10144299 | 0.91 | GAA (0.50) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17081033 | 0.90 | TSHR (0.47) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17447083 | 0.86 | GAA (0.49) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL12606666 | 0.85 | JAK2 (0.44) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL20481990 | 0.85 | PTPN2 (0.47) | HDAC3HDAC4HDAC1HDAC6TSHR | |
| SCHEMBL2180231 | 0.85 | GPR35 (0.67) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL17340892 | 0.85 | ALDH1A1 (0.63) | HDAC3HDAC4HDAC1HDAC6TSHR | |
| SCHEMBL4570574 | 0.82 | GAA (0.46) | GPR35HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL10174989 | 0.82 | JAK2 (0.39) | GPR35HDAC3HDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828903-B1 | OPTOELECTRONIC DEVICES COMPRISING POLYMERIC BLENDS | RAYNERGY TEK INC (TW) | 2017-11-01 | — | — | EP | disclosed |
| US-9312492-B2 | Polymeric blends and related optoelectronic devices | RAYNERGY TEK INC. (TW) | 2016-04-12 | — | — | US | disclosed |
| US-20160072070-A1 | POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES | POLYERA CORPORATION | 2016-03-10 | — | — | US | disclosed |
| US-20150171332-A1 | POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES | RAYNERGY TEK INC. (TW) | 2015-06-18 | — | — | US | disclosed |
| US-8906520-B2 | Sulfonated polythiophenes comprising fused ring repeat units | SOLVAY USA, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| US-8883958-B2 | Conjugated polymers and their use in optoelectronic devices | RAYNERGY TEK INC. (TW) | 2014-11-11 | — | — | US | disclosed |
| US-8841409-B2 | Conjugated polymers and their use in optoelectronic devices | POLYERA CORPORATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-8835598-B2 | Conjugated polymers and their use in optoelectronic devices | POLYERA CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| WO-2013142835-A1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORATION (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013142841-A1 | POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES | POLYERA CORPORATION (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013142845-A1 | CONJUGATED POLYMERS COMPRISING A BITHIOPHENE - IMIDE - BASED UNIT AND THEIR USE IN OPTOELECTRONIC DEVICES | POLYERA CORPORATION (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20130247991-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | RAYNERGY TEK INC. (TW) | 2013-09-26 | — | — | US | disclosed |
| US-20130247990-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | RAYNERGY TEK INC. (TW) | 2013-09-26 | — | — | US | disclosed |
| US-20130247992-A1 | Polymeric Blends and Related Optoelectronic Devices | RAYNERGY TEK INC. (TW) | 2013-09-26 | — | — | US | disclosed |
| US-20130248831-A1 | Conjugated Polymers and Their Use in Optoelectronic Devices | POLYERA CORPORATION (US) | 2013-09-26 | — | — | US | disclosed |
| EP-2595975-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | Corning Incorporated (US) | 2013-05-29 | — | — | EP | disclosed |
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED | 2012-01-26 | — | — | US | disclosed |
| WO-2012012278-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | CORNING INCORPORATED (US) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022116-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PATHOLOGICAL CONDITION(S) RELATED TO GPR35 AND/OR GPR35-HERG COMPLEX | GPR35, GPR65, GPR68 | GPR35 1/4885HDAC3 881/4885HDAC4 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.