Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543672 | 0.81 | CA1 (0.35) | BRD4CREBBPHPGD | |
| SCHEMBL3342928 | 0.72 | SIRT1 (0.38) | HPGD | |
| SCHEMBL2884627 | 0.70 | BRD4 (0.33) | BRD4CREBBP | |
| SCHEMBL2247994 | 0.69 | MAOA (0.41) | BRD4CREBBPTDP1SMN1; SMN2MAOA | |
| SCHEMBL3487104 | 0.69 | MAOA (0.41) | BRD4CREBBPTDP1SMN1; SMN2MAOA | |
| SCHEMBL2885484 | 0.69 | BRD4 (0.32) | BRD4CREBBP | |
| SCHEMBL2884998 | 0.69 | BRD4 (0.32) | BRD4CREBBP | |
| SCHEMBL8470150 | 0.67 | BRD4 (0.50) | BRD4CREBBPTDP1MAOAHPGD | |
| SCHEMBL765957 | 0.67 | BRD4 (0.50) | BRD4CREBBPTDP1MAOAHPGD | |
| SCHEMBL8471197 | 0.67 | BRD4 (0.50) | BRD4CREBBPTDP1MAOAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018153508-A2 | SULFOXIMINE GLYCOSIDASE INHIBITORS | Asceneuron S.A. (CH) | 2018-08-30 | — | — | WO | disclosed |