Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482542 | 0.98 | ITGB1 (0.41) | ITGB1ITGA4PPARAPPARGKDM4E | |
| SCHEMBL20482266 | 0.87 | PPARA (0.36) | PPARAPPARGKDM4EMAPTMAPK1 | |
| SCHEMBL20482551 | 0.87 | KMT2A (0.49) | KDM4EMEN1KMT2AMAPTATM | |
| SCHEMBL4504503 | 0.85 | HSD11B1 (0.41) | ITGB1ITGA4PPARGKDM4EMEN1 | |
| SCHEMBL20482558 | 0.82 | MEN1 (0.45) | PPARAPPARGMEN1KMT2AMAPT | |
| SCHEMBL20482573 | 0.82 | ITGB1 (0.46) | ITGB1ITGA4MEN1KMT2AALDH1A1 | |
| SCHEMBL20482458 | 0.81 | HPGD (0.47) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20482585 | 0.81 | L3MBTL1 (0.36) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL20482612 | 0.80 | KDM4E (0.36) | KDM4EMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20482537 | 0.79 | REN (0.43) | ITGB1ITGA4PPARAALDH1A1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |