Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482392 | 0.83 | ALDH1A1 (0.51) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL20482637 | 0.80 | KMT2A (0.48) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL6627953 | 0.80 | ALDH1A1 (0.70) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL6311126 | 0.79 | POLB (0.54) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL20482551 | 0.78 | KMT2A (0.49) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL28915350 | 0.78 | MEN1 (0.72) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL4716099 | 0.78 | FPR2 (0.55) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL3718479 | 0.77 | KDM4E (0.64) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL15692863 | 0.77 | HSD11B1 (0.58) | KMT2AMEN1POLBGAAALDH1A1 | |
| SCHEMBL27350053 | 0.77 | MEN1 (0.53) | KMT2AMEN1POLBGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |