Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28424180 | 0.81 | MAOB (0.38) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL28099521 | 0.79 | DPP4 (0.33) | DPP4DPP8 | |
| SCHEMBL291792 | 0.76 | ALDH1A1 (0.46) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL29833702 | 0.76 | ALDH1A1 (0.46) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL3692332 | 0.76 | CA2 (0.40) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL1603242 | 0.75 | TRPA1 (0.42) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL27721857 | 0.74 | TRPA1 (0.45) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL1194487 | 0.73 | CA2 (0.41) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL8679577 | 0.73 | PDCD1 (0.50) | PDCD1CD274CA2ALDH1A1TSHR | |
| SCHEMBL27908557 | 0.73 | CA2 (0.41) | PDCD1CD274CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073655-A1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011073653-A1 | IMPROVED CARBONYLATION PROCESS | LUCITE INTERNATIONAL UK LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |