Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15373349 | 0.79 | TRPA1 (0.38) | ALDH1A1TRPA1HPGDMAPTL3MBTL1 | |
| SCHEMBL13773364 | 0.79 | TSHR (0.41) | ALDH1A1KDM4EHPGDMAPTPOLB | |
| SCHEMBL27951807 | 0.78 | MEN1 (0.35) | ALDH1A1ATMKMT2AMEN1HSP90AA1 | |
| SCHEMBL16774460 | 0.76 | CYP3A4 (0.43) | F2RCYP3A4PTGS2TUBB4ATUBB | |
| SCHEMBL8747532 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TRPA1GABRA1GABRB2KDM4E | |
| SCHEMBL22914949 | 0.76 | TRPA1 (0.45) | ALDH1A1TRPA1KDM4EHSD17B10HPGD | |
| SCHEMBL28142794 | 0.76 | CD44 (0.45) | ALDH1A1POLBL3MBTL1KMT2AMEN1 | |
| SCHEMBL14217217 | 0.76 | CYP1A2 (0.52) | ALDH1A1HSD17B10HPGDL3MBTL1F2R | |
| SCHEMBL13808092 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL27469034 | 0.76 | ALDH1A1 (0.33) | ALDH1A1F2RTUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369726-B1 | METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL | SUMITOMO CHEMICAL CO (JP) | 2020-08-26 | — | — | EP | disclosed |
| CN-108349884-B | Process for producing 2-amino-4-substituted phenol | 住友化学株式会社 | 2020-04-21 | — | — | CN | disclosed |
| US-10093617-B1 | Method for producing 2-amino-4-substituted phenol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-10-09 | — | — | US | disclosed |
| US-20180282267-A1 | METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-10-04 | — | — | US | disclosed |
| EP-3369726-A1 | METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL | Sumitomo Chemical Company, Limited (JP) | 2018-09-05 | — | — | EP | disclosed |
| CN-108349884-A | Process for producing 2-amino-4-substituted phenol | 住友化学株式会社 | 2018-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10093617-B1 | Method for producing 2-amino-4-substituted phenol | PAH, ASNS, AVPR2 | ALDH1A1 297/4885TRPA1 962/4885GABRA1 2665/4885 |
| US-20180282267-A1 | METHOD FOR PRODUCING 2-AMINO-4-SUBSTITUTED PHENOL | PAH, ASNS, AVPR2 | ALDH1A1 297/4885TRPA1 962/4885GABRA1 2665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.