Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.49 |
| ▸ | XIAP | P98170 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20485174 | 1.00 | OPRM1 (0.49) | OPRM1XIAPOPRK1EPHA2F2 | |
| SCHEMBL20485176 | 1.00 | OPRM1 (0.49) | OPRM1XIAPOPRK1EPHA2F2 | |
| SCHEMBL18619636 | 0.91 | MALT1 (0.55) | OPRM1OPRK1EPHA2F2 | |
| SCHEMBL18619514 | 0.90 | ACE (0.48) | OPRM1 | |
| SCHEMBL20485183 | 0.88 | MALT1 (0.43) | OPRM1OPRK1F2OPRD1 | |
| SCHEMBL20485185 | 0.88 | MALT1 (0.43) | OPRM1OPRK1F2OPRD1 | |
| SCHEMBL20485181 | 0.88 | MALT1 (0.43) | OPRM1OPRK1F2OPRD1 | |
| SCHEMBL20484562 | 0.85 | OPRM1 (0.43) | OPRM1OPRK1 | |
| SCHEMBL20484560 | 0.85 | OPRM1 (0.43) | OPRM1OPRK1 | |
| SCHEMBL20484563 | 0.85 | OPRM1 (0.43) | OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | MALT1, BCL3, BCL6 | OPRM1 4510/4885XIAP 117/4885OPRK1 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.