SCHEMBL204854

SCHEMBL204854

CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(OS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
KDM4E B2RXH2 2/20 0.39
POLB P06746 1/20 0.39
ALDH1A1 P00352 6/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.37
HTT P42858 2/20 0.37
EYA2 O00167 1/20 0.37
GAA P10253 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
MTNR1B P49286 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9152637 1.00 MAPT (0.44) MAPTKDM4EPOLBALDH1A1LMNA
SCHEMBL29709963 1.00 MAPT (0.44) MAPTKDM4EPOLBALDH1A1LMNA
SCHEMBL2953361 0.91 MAPT (0.45) MAPTKDM4EPOLBALDH1A1LMNA
SCHEMBL2953357 0.91 MAPT (0.45) MAPTKDM4EPOLBALDH1A1LMNA
SCHEMBL7131299 0.90 SMN1; SMN2 (0.42) MAPTKDM4EPOLBALDH1A1LMNA
SCHEMBL9150477 0.86 RAB9A (0.46) KDM4EPOLBALDH1A1RAB9AHTT
SCHEMBL9150478 0.86 RAB9A (0.46) KDM4EPOLBALDH1A1RAB9AHTT
SCHEMBL10390055 0.85 POLB (0.48) KDM4EPOLBALDH1A1SMN1; SMN2RAB9A
SCHEMBL10390057 0.85 POLB (0.48) KDM4EPOLBALDH1A1SMN1; SMN2RAB9A
SCHEMBL9152578 0.85 KDM4E (0.36) MAPTKDM4EPOLBRAB9APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 WO disclosed
EP-2749167-A1 Formulation for the antimicrobial treatment of polyvinyl chloride compositions Sanitized AG (CH) 2014-07-02 EP disclosed
EP-2670239-A1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS Sanitized AG (CH) 2013-12-11 EP disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
WO-2012104146-A1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2012-08-09 WO disclosed
EP-0714420-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AG (DE) 1996-06-05 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
US-5468857-A Phenylmethoxypropenoic esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-11-21 US disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995011786-A1 TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-05-04 WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed
US-5334748-A A methyl 2-aryl heterofunctional phenoxyphenyl-3-methoxy-propenoate compound; treating the plant diseases IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 MAPT 3249/4885KDM4E 1828/4885POLB 1822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.