SCHEMBL2048624

SCHEMBL2048624

CC(=O)ON=C(C)CC(CC(C)=NOC(C)=O)=NOC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2048622 1.00 PKM (0.35) PKMALDH1A1HTT
SCHEMBL9900525 0.94 HTT (0.37) PKMALDH1A1HTT
SCHEMBL9900527 0.94 HTT (0.37) PKMALDH1A1HTT
SCHEMBL2051215 0.89 ALDH1A1 (0.36) PKMALDH1A1HTT
SCHEMBL2051216 0.89 ALDH1A1 (0.36) PKMALDH1A1HTT
SCHEMBL2051966 0.87 ALDH1A1 (0.40) PKMALDH1A1HTT
SCHEMBL2051967 0.87 ALDH1A1 (0.40) PKMALDH1A1HTT
SCHEMBL9898646 0.83 HTT (0.48) PKMALDH1A1HTT
SCHEMBL9898648 0.83 HTT (0.48) PKMALDH1A1HTT
SCHEMBL4913039 0.78 PKM (0.33) PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed