Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900525 | 1.00 | HTT (0.37) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL2048624 | 0.94 | PKM (0.35) | HTTPKMALDH1A1 | |
| SCHEMBL2048622 | 0.94 | PKM (0.35) | HTTPKMALDH1A1 | |
| SCHEMBL2051215 | 0.88 | ALDH1A1 (0.36) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL2051216 | 0.88 | ALDH1A1 (0.36) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL9898648 | 0.87 | HTT (0.48) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL9898646 | 0.87 | HTT (0.48) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL2051967 | 0.82 | ALDH1A1 (0.40) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL2051966 | 0.82 | ALDH1A1 (0.40) | HTTMGAMGAASIMGAM2 | |
| SCHEMBL9900691 | 0.81 | HTT (0.38) | HTTMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |