SCHEMBL2048919

SCHEMBL2048919

COc1ccc(Cl)cc1Oc1nnc(Cl)cc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.39
SLC6A3 Q01959 3/20 0.39
MAPT P10636 3/20 0.39
TTR P02766 2/20 0.39
HPGD P15428 2/20 0.39
NR1I2 O75469 1/20 0.39
LMNA P02545 1/20 0.39
PGR P06401 1/20 0.39
HSP90AA1 P07900 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
HSPA5 P11021 1/20 0.39
CBR1 P16152 1/20 0.39
TBXA2R P21731 1/20 0.39
AGTR1 P30556 1/20 0.39
KCNMA1 Q12791 2/20 0.39
CXCL12 P48061 1/20 0.39
SLC6A4 P31645 3/20 0.39
AR P10275 1/20 0.39
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2045078 0.87 ACHE (0.49) MAPTHPGDKCNMA1ARALDH1A1
SCHEMBL2047981 0.87 CA12 (0.49) MAPTHPGDLMNAALDH1A1KDM4E
SCHEMBL2050928 0.85 WDR5 (0.38) MAPTHPGDLMNAWDR5ALDH1A1
SCHEMBL2049495 0.85 RAB9A (0.39) MAPTALDH1A1KMT2AMEN1NPC1
SCHEMBL2053013 0.84 CA1 (0.44) MAPTHPGDLMNAHSP90AA1ALDH1A1
SCHEMBL2049438 0.84 TTR (0.57) SLC6A2SLC6A3MAPTTTRHPGD
SCHEMBL2051526 0.83 CYP1A2 (0.46) SLC6A2SLC6A3MAPTTTRHPGD
SCHEMBL2049817 0.83 NR1I2 (0.37) SLC6A2SLC6A3MAPTTTRHPGD
SCHEMBL2044712 0.82 AR (0.44) MAPTSLC6A4ARALDH1A1KMT2A
SCHEMBL2045892 0.81 MAPT (0.52) MAPTLMNAKDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7964531-B2 3-phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2011-06-21 US disclosed
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same MITSUI CHEMICALS AGRO, INC. (JP) 2010-02-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041555-A1 3-Phenoxy-4-pyridazinol derivatives and herbicidal composition containing the same CBR3, DDT, CBR1 SLC6A2 3620/4885SLC6A3 1443/4885MAPT 4175/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 SLC6A2 3617/4885SLC6A3 1647/4885MAPT 3630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.