SCHEMBL2048990

SCHEMBL2048990

c1ccc(-c2cccc3c2Cc2c(-c4ccccc4)cccc2-3)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.47
PARP10 Q53GL7 1/20 0.47
PARP11 Q9NR21 1/20 0.47
ALDH1A1 P00352 4/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 1/20 0.44
BCL2L1 Q07817 1/20 0.44
CYP2A6 P11509 1/20 0.44
MAPK1 P28482 1/20 0.44
ANPEP P15144 2/20 0.43
IL1RN P18510 1/20 0.43
ERAP2 Q6P179 1/20 0.43
ERAP1 Q9NZ08 1/20 0.43
HTR1A P08908 2/20 0.41
HTR7 P34969 2/20 0.41
BACE1 P56817 1/20 0.40
DPP4 P27487 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809707 0.86 PNMT (0.53) PRCPPARP10PARP11ANPEPIL1RN
SCHEMBL29401802 0.86 PNMT (0.53) PRCPPARP10PARP11ANPEPIL1RN
SCHEMBL70992 0.86 PNMT (0.53) PRCPPARP10PARP11ANPEPIL1RN
SCHEMBL17467311 0.85 L3MBTL1 (0.45) PRCPPARP10PARP11ALDH1A1HSD17B10
SCHEMBL27718430 0.84 PNMT (0.52) PRCPPARP10PARP11ANPEPIL1RN
Bromide SCHEMBL15404509 0.84 PNMT (0.52) PRCPPARP10PARP11ANPEPIL1RN
SCHEMBL17467303 0.84 TSHR (0.45) PRCPPARP10PARP11ALDH1A1HSD17B10
SCHEMBL17467310 0.84 L3MBTL1 (0.44) PRCPPARP10PARP11ALDH1A1HSD17B10
SCHEMBL17467333 0.84 L3MBTL1 (0.44) PRCPPARP10PARP11ALDH1A1HSD17B10
SCHEMBL17467336 0.84 L3MBTL1 (0.44) PRCPPARP10PARP11ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250136738-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2025-05-01 US claimed
EP-4501992-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2025-02-05 EP claimed
CN-118660920-A Curable composition, cured product, molded body, and optical material 三井化学株式会社 2024-09-17 CN claimed
WO-2023188978-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL 三井化学株式会社 2023-10-05 WO claimed
US-20250136738-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2025-05-01 US disclosed
US-20250115689-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION MITSUI CHEMICALS, INC. (JP) 2025-04-10 US disclosed
EP-4501992-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2025-02-05 EP disclosed
EP-4501978-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION Mitsui Chemicals, Inc. (JP) 2025-02-05 EP disclosed
CN-118660920-A Curable composition, cured product, molded body, and optical material 三井化学株式会社 2024-09-17 CN disclosed
CN-118591569-A Multifunctional (meth) acrylic thioester composition, curable composition, cured product, molded article, optical material, and method for producing multifunctional (meth) acrylic thioester composition 三井化学株式会社 2024-09-03 CN disclosed
WO-2023188968-A1 POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION, CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, OPTICAL MATERIAL, AND METHOD FOR PRODUCING POLYFUNCTIONAL (METH)ACRYLATE THIOESTER COMPOSITION 三井化学株式会社 2023-10-05 WO disclosed
WO-2023188978-A1 CURABLE COMPOSITION, CURED PRODUCT, MOLDED BODY, AND OPTICAL MATERIAL 三井化学株式会社 2023-10-05 WO disclosed
WO-2023074471-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER 帝人株式会社 2023-05-04 WO disclosed
US-20230091908-A1 FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME OSAKA GAS CHEMICALS CO., LTD. (JP) 2023-03-23 US disclosed
US-20230051676-A1 POLYCARBONATE AND METHOD FOR PRODUCING POLYCARBONATE TEIJIN LIMITED (JP) 2023-02-16 US disclosed
CN-114901628-A Fluorene derivative, preparation method and application thereof 大阪燃气化学有限公司 2022-08-12 CN disclosed
US-20110152463-A1 RESIN COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 US disclosed
US-20100093957-A1 METHOD FOR PRODUCING BUTENE-ETHYLENE COPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-15 US disclosed
EP-2123685-A1 METHOD FOR PRODUCING BUTENE-ETHYLENE COPOLYMER Sumitomo Chemical Company, Limited (JP) 2009-11-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230091908-A1 FLUORENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND APPLICATION OF SAME ADORA2B, ADORA2A, ADORA1 PRCP 4868/4885PARP10 346/4885PARP11 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.