SCHEMBL2049219

SCHEMBL2049219

CC/C=C(\NCC)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.35
GRIK2 Q13002 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.32
KDM4E B2RXH2 1/20 0.32
FAAH O00519 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL629548 0.84 GRIK1 (0.34) GRIK1GRIK2
SCHEMBL5693362 0.82 GRIK1 (0.39) GRIK1GRIK2
SCHEMBL7639946 0.80 FAAH (0.43) KMT2AFAAHALDH1A1
SCHEMBL5693448 0.80 MMP1 (0.31) MMP1MMP2MMP3MMP9MMP8
SCHEMBL4222788 0.80
SCHEMBL4291255 0.80
SCHEMBL2349984 0.78
SCHEMBL22739266 0.78
SCHEMBL28058398 0.77 TET2 (0.34) MMP1MMP2MMP3MMP9MMP8
SCHEMBL4939289 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110213099-A1 Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer PATIL DAMODAR R 2011-09-01 US claimed
US-7999040-B2 Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer NANOCHEM SOLUTIONS, INC. (US) 2011-08-16 US claimed
EP-2326672-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY (ASPARTATE) AND THE RESULTING GRAFT COPOLYMER Nanochem Solutions, Inc. (US) 2011-06-01 EP claimed
WO-2010030323-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY (ASPARTATE) AND THE RESULTING GRAFT COPOLYMER NANOCHEM SOLUTIONS, INC. (US) 2010-03-18 WO claimed
US-20090326165-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY(ASPARTATE) AND THE RESULTING GRAFT COPOLYMER NANOCHEM SOLUTIONS, INC. 2009-12-31 US claimed
US-8202946-B2 Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer NANOCHEM SOLUTIONS, INC. (US) 2012-06-19 US disclosed
US-20110213099-A1 Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer PATIL DAMODAR R 2011-09-01 US disclosed
US-7999040-B2 Method of making graft copolymers from sodium poly(aspartate) and the resulting graft copolymer NANOCHEM SOLUTIONS, INC. (US) 2011-08-16 US disclosed
EP-2326672-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY (ASPARTATE) AND THE RESULTING GRAFT COPOLYMER Nanochem Solutions, Inc. (US) 2011-06-01 EP disclosed
WO-2010030323-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY (ASPARTATE) AND THE RESULTING GRAFT COPOLYMER NANOCHEM SOLUTIONS, INC. (US) 2010-03-18 WO disclosed
US-20090326165-A1 METHOD OF MAKING GRAFT COPOLYMERS FROM SODIUM POLY(ASPARTATE) AND THE RESULTING GRAFT COPOLYMER NANOCHEM SOLUTIONS, INC. 2009-12-31 US disclosed
EP-1487882-B1 BASE POLYMER OBTAINED BY HYDROGENATION STOCKHAUSEN CHEM FAB GMBH (DE) 2006-05-24 EP disclosed
US-20050215756-A1 Basic polymer obtained by hydrogenation STOCKHAUSEN GMBH (DE) 2005-09-29 US disclosed