SCHEMBL629548

SCHEMBL629548

CC/C=C(\NCO)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.34
GRIK2 Q13002 1/20 0.34
EP300 Q09472 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2049219 0.84 GRIK1 (0.35) GRIK1GRIK2
SCHEMBL7639946 0.78 FAAH (0.43)
SCHEMBL22739266 0.76
SCHEMBL2349984 0.76
SCHEMBL4939289 0.73
SCHEMBL28890860 0.71 CYP2C9 (0.53)
SCHEMBL2190700 0.71 GRIK1 (0.37) GRIK1GRIK2
SCHEMBL1847277 0.71 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL11667050 0.70 GRIK1 (0.36) GRIK1GRIK2
SCHEMBL28358483 0.68 EGLN1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549692-B1 NANOPARTICLES, METHOD FOR MODIFYING THEIR SURFACES, DISPERSION OF NANOPARTICLES, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF BASF COATINGS GMBH (DE) 2012-02-22 EP disclosed
EP-1549692-A1 NANOPARTICLES, METHOD FOR MODIFYING THEIR SURFACES, DISPERSION OF NANOPARTICLES, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF BASF Coatings AG (DE) 2005-07-06 EP disclosed
WO-2004035649-A1 NANOPARTICLES, METHOD FOR MODIFYING THEIR SURFACES, DISPERSION OF NANOPARTICLES, METHOD FOR THE PRODUCTION AND THE UTILIZATION THEREOF BASF COATINGS AG (DE) 2004-04-29 WO disclosed