SCHEMBL2044910

SCHEMBL2044910

CC(CC(Cc1ccccc1)=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1)=NO[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 3/20 0.36
GAA P10253 3/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 4/20 0.35
MAPT P10636 3/20 0.35
MEN1 O00255 2/20 0.35
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2044909 1.00 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2049446 0.88 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2049447 0.88 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2044132 0.85 MAOB (0.33) SMN1; SMN2L3MBTL1LMNAHTTMAPT
SCHEMBL2044130 0.85 MAOB (0.33) SMN1; SMN2L3MBTL1LMNAHTTMAPT
SCHEMBL2050543 0.84 LMNA (0.36) L3MBTL1LMNAHTTKDM4EMAPT
SCHEMBL2050541 0.84 LMNA (0.36) L3MBTL1LMNAHTTKDM4EMAPT
SCHEMBL9898021 0.84 KDM4E (0.40) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL9898022 0.84 KDM4E (0.40) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL9899203 0.82 MAPT (0.33) ALDH1A1SMN1; SMN2L3MBTL1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed