Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546867 | 0.88 | SIGMAR1 (0.50) | SIGMAR1EP300KAT5KAT8HSD11B1 | |
| SCHEMBL8095518 | 0.87 | TLR8 (0.44) | SIGMAR1HSD11B1HTTCYSLTR2CYSLTR1 | |
| SCHEMBL12506239 | 0.86 | HTR2A (0.47) | SIGMAR1KCNH2DRD2HTR1A | |
| SCHEMBL819273 | 0.86 | LIPG (0.45) | EP300KAT5KAT8HTTCYSLTR2 | |
| SCHEMBL10917103 | 0.86 | KCNH2 (0.54) | SIGMAR1EP300KAT5KAT8HSD11B1 | |
| Ammonia Solution, Strong SCHEMBL9810933 | 0.84 | LIPG (0.44) | EP300KAT5KAT8HTTCYSLTR2 | |
| Water SCHEMBL27341058 | 0.84 | LIPG (0.44) | EP300KAT5KAT8HTTCYSLTR2 | |
| SCHEMBL8087736 | 0.83 | TLR8 (0.43) | SIGMAR1HTTCYSLTR2CYSLTR1LIPG | |
| SCHEMBL29138369 | 0.83 | KAT8 (0.49) | EP300KAT5KAT8DRD2OPRM1 | |
| SCHEMBL8095162 | 0.82 | TLR8 (0.49) | SIGMAR1EP300KAT5KAT8CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822622-B2 | Two-component polyurethane coating compositions | AXALTA COATING SYSTEMS IP CO., LLC (US) | 2014-09-02 | — | — | US | disclosed |
| EP-2507282-B1 | TWO-COMPONENT POLYURETHANE COATING COMPOSITIONS | DU PONT (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-2507282-A1 | TWO-COMPONENT POLYURETHANE COATING COMPOSITIONS | E.I. Du Pont De Nemours And Company (US) | 2012-10-10 | — | — | EP | disclosed |
| US-20120237688-A1 | TWO-COMPONENT POLYURETHANE COATING COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-09-20 | — | — | US | disclosed |
| WO-2011068826-A1 | TWO-COMPONENT POLYURETHANE COATING COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20030199663-A1 | Delayed action tin catalysts | CROMPTON GMBH (DE) | 2003-10-23 | — | — | US | disclosed |
| EP-1354903-A1 | Delayed action tin catalysts | Crompton GmbH (DE) | 2003-10-22 | — | — | EP | disclosed |