⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320817 | 0.80 | — | — | |
| SCHEMBL330689 | 0.72 | — | — | |
| SCHEMBL30931747 | 0.72 | — | — | |
| SCHEMBL1039840 | 0.72 | — | — | |
| SCHEMBL329345 | 0.72 | — | — | |
| SCHEMBL943208 | 0.72 | CYP1A2 (0.38) | — | |
| SCHEMBL57842 | 0.71 | — | — | |
| Phosphine SCHEMBL22230553 | 0.70 | TAAR1 (0.46) | — | |
| SCHEMBL8978635 | 0.70 | CFD (0.47) | — | |
| SCHEMBL18680747 | 0.70 | CYP1A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272418-A | Triazole compound and its preparation method and application | 山东大学 | 2019-09-24 | — | — | CN | claimed |
| CN-110088102-A | A kind of nitrogen-containing hetero cyclics, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-109790149-A | PHENOXYTRIAZOLES | 豪夫迈·罗氏有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-102459158-B | Novel amide and amidine derivatives and use thereof | ABBVIE (US) | 2015-11-25 | — | — | CN | claimed |
| CN-104884451-A | Pyridinone and pyridazinone derivatives | ABBVIE INC | 2015-09-02 | — | — | CN | claimed |
| CN-104292229-A | 2-phenoxy pyrimidinone analogues | NEUROGEN CORP | 2015-01-21 | — | — | CN | claimed |
| CN-104271128-A | Use of aminoacetonitrile derivatives against endoparasites | AH USA 42 LLC | 2015-01-07 | — | — | CN | claimed |
| CN-102015636-B | Azetidines and cyclobutanes as histamine H3 receptor antagonists | EVOTEC NEUROSCIENCES GMBH | 2014-08-13 | — | — | CN | claimed |
| CN-103772239-A | Novel amide and amidine derivatives and uses thereof | ABBVIE INC | 2014-05-07 | — | — | CN | claimed |
| CN-101528731-B | Aminopyridine derivatives having AuroraA selective inhibitory action | MSD KK | 2014-05-07 | — | — | CN | claimed |
| US-7705158-B2 | Inhibitors of ion channels | ICAGEN, INC. (US) | 2010-04-27 | — | — | US | claimed |
| EP-1653960-A4 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN INC (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1653960-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN INC. (US) | 2006-05-10 | — | — | EP | claimed |
| US-20050215526-A1 | Melanin concentrating hormone receptor antagonist | AMGEN, INC. | 2005-09-29 | — | — | US | claimed |
| WO-2005019167-A2 | MELANIN CONCENTRATING HORMONE RECEPTOR ANTAGONIST | AMGEN, INC. (US) | 2005-03-03 | — | — | WO | claimed |
| US-20040044048-A1 | (R)-chiral halogenated 1-substitutedamino-(n+1)-alkanols useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2004-03-04 | — | — | US | claimed |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-10-09 | — | — | US | claimed |
| US-6544974-B2 | Treating atherosclerosis and other coronary artery diseases. | G.D. SEARLE & CO. | 2003-04-08 | — | — | US | claimed |
| US-6521607-B1 | Preventing coronary artery disease | PHARMACIA CORPORATION | 2003-02-18 | — | — | US | claimed |
| US-20010018446-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2001-08-30 | — | — | US | claimed |