SCHEMBL8978635

SCHEMBL8978635

Fc1c(Cl)cccc1C(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFD P00746 1/20 0.47
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 1/20 0.42
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
PNMT P11086 1/20 0.39
LMNA P02545 3/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
TSHR P16473 4/20 0.35
HIF1A Q16665 2/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NR1I2 O75469 1/20 0.35
ABCB11 O95342 1/20 0.35
NR3C1 P04150 1/20 0.35
PGR P06401 1/20 0.35
ADRA2A P08913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8216990 0.79 CFD (0.50) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL22124021 0.79 CFD (0.46) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL3460850 0.77 CFD (0.53) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL23832498 0.77 CFD (0.41) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL320817 0.76
SCHEMBL23613124 0.76 CFD (0.47) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL22904307 0.76 P2RX7 (0.50) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL24989692 0.76 CFD (0.47) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL21789838 0.76 CFD (0.47) CFDCYP1A2CYP2A6CYP3A4CYP2D6
SCHEMBL20764909 0.76 CFD (0.44) CFDCYP1A2CYP2A6CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0555698-B1 Process for the preparation of possibly substituted benzaldehydes BAYER AG (DE) 1996-05-08 EP disclosed
EP-0555698-A1 Process for the preparation of possibly substituted benzaldehydes BAYER AG (DE) 1993-08-18 EP disclosed