Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522292 | 0.69 | KDM4E (0.44) | TSHRKMT2AALOX15HSD17B10KDM4E | |
| SCHEMBL29288162 | 0.68 | MAPT (0.47) | LMNATSHRNFKB1PMP22MAPT | |
| SCHEMBL10594848 | 0.66 | FNTA (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL15272171 | 0.66 | EP300 (0.56) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL5320548 | 0.66 | LMNA (0.48) | LMNASLC22A6TSHRNFKB1PMP22 | |
| Hydrochloric Acid SCHEMBL6339249 | 0.64 | LMNA (0.46) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL15571633 | 0.64 | LMNA (0.40) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL18035212 | 0.64 | PPARG (0.67) | LMNASLC22A6MAPTPPARGTOP1 | |
| SCHEMBL4453779 | 0.64 | PPARG (0.67) | LMNASLC22A6MAPTPPARGTOP1 | |
| SCHEMBL4453776 | 0.64 | PPARG (0.67) | LMNASLC22A6MAPTPPARGTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032344-B1 | MEDICAL DEVICES AND RELATED SYSTEMS AND METHODS | BOSTON SCIENT LTD (BB) | 2011-06-22 | — | — | EP | disclosed |
| US-7718106-B2 | Medical devices and related systems and methods | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080097396-A1 | Medical devices and related systems and methods | BOSTON SCIENTIFIC SCIMED, INC. | 2008-04-24 | — | — | US | disclosed |