Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6339249 | 0.98 | LMNA (0.46) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL8773549 | 0.91 | MAPT (0.56) | LMNATSHRNFKB1PMP22MAPT | |
| SCHEMBL6252065 | 0.91 | MAPT (0.56) | LMNATSHRNFKB1PMP22MAPT | |
| SCHEMBL6821345 | 0.91 | MAPT (0.56) | LMNATSHRNFKB1PMP22MAPT | |
| Hydrochloric Acid SCHEMBL6848395 | 0.89 | MAPT (0.54) | LMNATSHRNFKB1PMP22MAPT | |
| SCHEMBL7752450 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL7747372 | 0.82 | LMNA (0.40) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL6339247 | 0.78 | ALDH1A1 (0.42) | TSHRALDH1A1TP53 | |
| SCHEMBL10594848 | 0.75 | FNTA (0.60) | LMNASLC22A6TSHRNFKB1PMP22 | |
| SCHEMBL15272171 | 0.75 | EP300 (0.56) | LMNASLC22A6TSHRNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0577555-B1 | Derivatives of carboxylic acids | CIBA GEIGY AG (CH) | 1997-11-05 | — | — | EP | claimed |
| WO-2007089455-A1 | FLUOROALKENYL DERIVATIVES AS INSECTICIDES AND NEMATICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
| US-6852888-B2 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2005-02-08 | — | — | US | disclosed |
| EP-1084100-B1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| WO-2004052872-A1 | HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2004-06-24 | — | — | WO | disclosed |
| EP-0661289-B1 | Vinyl carboxamide derivatives as insecticides and acaricides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-03 | — | — | EP | disclosed |
| US-20030216467-A1 | Carboxylic acid derivatives | SYNGENTA CROP PROTECTION, INC. (FORMERLY KNOWN AS NOVARTIS CROP PROTECTION, INC.) | 2003-11-20 | — | — | US | disclosed |
| EP-1084100-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | Novartis AG (CH) | 2001-03-21 | — | — | EP | disclosed |
| EP-0986534-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2000-03-22 | — | — | EP | disclosed |
| WO-1999062866-A1 | DIFLUOROALKENCARBOXANILIDES AND PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 1999-12-09 | — | — | WO | disclosed |
| WO-1998055448-A2 | FLUOROALKENE CARBOXYLIC ACID DERIVATIVES, METHOD FOR PRODUCING SAID DERIVATIVES, AND INSECTICIDAL AGENTS CONTAINING THE SAME | NOVARTIS AG (CH) | 1998-12-10 | — | — | WO | disclosed |
| US-5763481-A | PESTICIDES; INSECTICIDES, MITICIDES | NOVARTIS CORPROATION (US) | 1998-06-09 | — | — | US | disclosed |
| US-5545630-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1996-08-13 | — | — | US | disclosed |
| EP-0661289-A1 | Vinyl carboxamide derivatives as insecticides and acaricides | CIBA-GEIGY AG (CH) | 1995-07-05 | — | — | EP | disclosed |
| US-5248810-A | Insecticides, acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0432861-A1 | Halogenated olefines, process for the preparation thereof and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216467-A1 | Carboxylic acid derivatives | CLIC1, CNPY3, HCFC1 | LMNA 533/4885SLC22A6 1687/4885TSHR 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.