SCHEMBL204998

SCHEMBL204998

CO/C=C(/C(=O)OC)c1ccccc1Oc1cccc(Oc2cccc(C#N)c2)c1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.38
KDM4E B2RXH2 2/20 0.38
POLB P06746 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37
P4HB P07237 1/20 0.37
MTNR1B P49286 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
EPAS1 Q99814 1/20 0.36
MCHR1 Q99705 1/20 0.36
VEGFA P15692 1/20 0.36
JAK2 O60674 1/20 0.36
JAK1 P23458 1/20 0.36
JAK3 P52333 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29356020 1.00 AR (0.38) ARKDM4EPOLBRXFP1P4HB
SCHEMBL30051463 0.90 KDM4E (0.41) ARKDM4EPOLBRXFP1P4HB
SCHEMBL2852472 0.90 KDM4E (0.41) ARKDM4EPOLBRXFP1P4HB
SCHEMBL2852480 0.90 KDM4E (0.41) ARKDM4EPOLBRXFP1P4HB
SCHEMBL29604075 0.90 RXFP1 (0.41) ARKDM4EPOLBRXFP1MTNR1B
SCHEMBL9150478 0.87 RAB9A (0.46) KDM4EPOLBMTNR1B
SCHEMBL9150477 0.87 RAB9A (0.46) KDM4EPOLBMTNR1B
SCHEMBL10390055 0.86 POLB (0.48) KDM4EPOLBMTNR1BSMN1; SMN2
SCHEMBL10390057 0.86 POLB (0.48) KDM4EPOLBMTNR1BSMN1; SMN2
SCHEMBL9151765 0.86 POLB (0.51) KDM4EPOLBMTNR1BSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
CN-111194314-B Microbicidal pyridine amide derivative 先正达参股股份有限公司 2022-12-30 CN disclosed
CN-108463460-B Microbiocidal oxadiazole derivatives 先正达参股股份有限公司 2022-10-28 CN disclosed
CN-113873886-A Overcoat compositions 特洛伊公司 2021-12-31 CN disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
EP-2670239-B1 FORMULATION FOR THE ANTIMICROBIAL AND FUNGICIDAL TREATMENT OF POLYMERIC MATERIALS, IN PARTICULAR OF PAINTS AND COATINGS SANITIZED AG (CH) 2015-08-12 EP disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
WO-2014102228-A1 FORMULATION FOR THE ANTIMICROBIAL TREATMENT OF POLYMER COMPOSITIONS SANITIZED AG (CH) 2014-07-03 WO disclosed
EP-0730517-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AG (DE) 1996-09-11 EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed
EP-0714420-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AG (DE) 1996-06-05 EP disclosed
WO-1996010915-A1 INSECTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-04-18 WO disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995024997-A1 COMBINATIONS OF ACTIVE INSECTICIDE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-21 WO disclosed
WO-1995014558-A1 TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1995-06-01 WO disclosed
WO-1995006091-A1 MOULD-RESISTANT EMULSION PAINTS BAYER AKTIENGESELLSCHAFT (DE) 1995-03-02 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 AR 4850/4885KDM4E 1828/4885POLB 1822/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 AR 1662/4885KDM4E 852/4885POLB 4747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.