Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | GRM8 | O00222 | 1/20 | 0.72 |
| ▸ | GRM6 | O15303 | 1/20 | 0.72 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.72 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.72 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.72 |
| ▸ | GRM5 | P41594 | 1/20 | 0.72 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.72 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.72 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.72 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.72 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.72 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.72 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.72 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.72 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.72 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.72 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8000337 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL27400214 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL7258645 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL890044 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1079951 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1079952 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL8000334 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL2415481 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL21796040 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL6034319 | 0.98 | GSR (0.77) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2301 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4745244-A1 | ENGINEERING BIOLOGICAL CONTAINMENT SYSTEM AND METHOD | BGI Shenzhen (CN) | 2026-05-20 | — | — | EP | claimed |
| US-20260125432-A1 | MALTOSE DEPENDENT DEGRONS, MALTOSE-RESPONSIVE PROMOTERS, STABILIZATION CONSTRUCTS, AND THEIR USE IN PRODUCTION OF NON-CATABOLIC COMPOUNDS | AMYRIS INC (US) | 2026-05-07 | — | — | US | claimed |
| WO-2025226744-A1 | SENESCENT CELL TARGETING T CELL RESPONSES BY EX VIVO GENERATED ANTIGEN PRESENTING CELLS | IMMORTA BIO, INC. (US) | 2025-10-30 | — | — | WO | claimed |
| CN-119955751-A | Curcumin compound synthetase CsPKS, gene and application | 四川天瓴基因快析科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-116555306-B | DPease gene, gene expression module and preparation method of D-psicose | 天津大学 | 2025-03-04 | — | — | CN | claimed |
| US-20250057865-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS | Vymedic, Inc. | 2025-02-20 | — | — | US | claimed |
| WO-2025038636-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS | Vymedic, Inc. (US) | 2025-02-20 | — | — | WO | claimed |
| WO-2025010715-A1 | ENGINEERING BIOLOGICAL CONTAINMENT SYSTEM AND METHOD | 深圳华大生命科学研究院 | 2025-01-16 | — | — | WO | claimed |
| US-12178874-B2 | Aflibercept formulations containing a lysine salt as tonicifying agent and uses thereof | JUST-EVOTEC BIOLOGICS, INC. (US) | 2024-12-31 | — | — | US | claimed |
| CN-119193656-A | Yeast cell model responding to umami signals and preparation method and application thereof | 上海交通大学 | 2024-12-27 | — | — | CN | claimed |
| EP-0477991-B1 | Process for producing crystals of salt of acidic amino acid and basic amino acid | KYOWA HAKKO KOGYO KK (JP) | 1994-12-28 | — | — | EP | claimed |
| WO-1994002140-A1 | PHARMACEUTICAL COMPOSITION CONTAINING ANTIULCER AGENT | ASTRA AKTIEBOLAG (SE) | 1994-02-03 | — | — | WO | claimed |
| EP-0246829-B1 | HTLV-III virus related peptides, antibodies to the peptides, vaccines, passive and active immunization against AIDS virus and diagnostic test for the serological detection of the AIDS virus | VIRAL TECHNOLOGIES INC (US) | 1994-01-19 | — | — | EP | claimed |
| EP-0477991-A1 | Process for producing crystals of salt of acidic amino acid and basic amino acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-04-01 | — | — | EP | claimed |
| EP-0340243-A1 | CC-1065 ANALOGS. | UPJOHN CO (US) | 1989-11-08 | — | — | EP | claimed |
| WO-1988004659-A2 | NOVEL CC-1065 ANALOGS | THE UPJOHN COMPANY (US) | 1988-06-30 | — | — | WO | claimed |
| EP-0246829-A2 | HTLV-III virus related peptides, antibodies to the peptides, vaccines, passive and active immunization against AIDS virus and diagnostic test for the serological detection of the AIDS virus | VIRAL TECHNOLOGIES, INC. (US) | 1987-11-25 | — | — | EP | claimed |
| US-4534881-A | Inhibition of inorganic or biological CaCO3 deposition by poly amino acid derivatives | UNIVERSITY OF SOUTH ALABAMA (US) | 1985-08-13 | — | — | US | claimed |
| US-4415590-A | Herpes treatment | BETAMED PHARMACEUTICALS, INC. (US) | 1983-11-15 | — | — | US | claimed |
| US-4052372-A | FROM LYSINE GLUTAMATE | SOCIETE D'ASSISTANCE TECHNIQUE POUR PRODUITS NESTLE S.A. (CH) | 1977-10-04 | — | — | US | claimed |