Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of D-Glutamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | GRM8 | O00222 | 1/20 | 0.72 |
| ▸ | GRM6 | O15303 | 1/20 | 0.72 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.72 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.72 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.72 |
| ▸ | GRM5 | P41594 | 1/20 | 0.72 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.72 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.72 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.72 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.72 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.72 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.72 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.72 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.72 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.72 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.72 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.72 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL8000337 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL27400214 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL7258645 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL890044 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL1079951 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL1079952 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL8000334 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL205003 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| D-Glutamate SCHEMBL21796040 | 1.00 | GSR (0.80) | GSRCYP1A2GRM8GRM6GRIN2D | |
| Lysine SCHEMBL6034319 | 0.98 | GSR (0.77) | GSRCYP1A2GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250057865-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS FOR HERPESVIRUS INFECTIONS | Vymedic, Inc. | 2025-02-20 | — | — | US | claimed |
| US-20240075048-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2024-03-07 | — | — | US | claimed |
| US-11826377-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2023-11-28 | — | — | US | claimed |
| US-20220323469-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2022-10-13 | — | — | US | claimed |
| CN-114988571-A | Carbon source carrier filler for denitrifying bacteria and preparation method | 嘉兴学院 | 2022-09-02 | — | — | CN | claimed |
| US-11224606-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2022-01-18 | — | — | US | claimed |
| US-20200108086-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2020-04-09 | — | — | US | claimed |
| US-10478447-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2019-11-19 | — | — | US | claimed |
| US-20180256618-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2018-09-13 | — | — | US | claimed |
| US-9907809-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2018-03-06 | — | — | US | claimed |
| US-20150272974-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC INC. | 2015-10-01 | — | — | US | claimed |
| US-9034834-B2 | Antiviral supplement formulations | VYMEDIC, LLC (US) | 2015-05-19 | — | — | US | claimed |
| EP-2362725-B1 | Antiviral supplement formulations | VYMEDIC LLC (US) | 2015-01-07 | — | — | EP | claimed |
| US-8394401-B2 | Antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine | AJINOMOTO CO., INC. (JP) | 2013-03-12 | — | — | US | claimed |
| CN-102557974-A | Method for preparing L-lysine composite salt | CHANGZHOU INST ENG TECH | 2012-07-11 | — | — | CN | claimed |
| CN-102264222-A | Antiviral tonic | — | 2011-11-30 | — | — | CN | claimed |
| US-20100113373-A1 | ANTIVIRAL SUPPLEMENT FORMULATIONS | VYMEDIC, LLC (US) | 2010-05-06 | — | — | US | claimed |
| WO-2025100523-A1 | METHOD FOR PRODUCING SOLID PREPARATION, AND TABLETS | 第一三共ヘルスケア株式会社 | 2025-05-15 | — | — | WO | disclosed |
| US-20050249781-A1 | Antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine | AJINOMOTO CO., LTD. (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1593312-A1 | Antiobesity or antihyperlipidemic food, feeding stuff or supplement containing lysine | Ajinomoto Co., Inc. (JP) | 2005-11-09 | — | — | EP | disclosed |