Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.54 |
| ▸ | SCN4A | P35499 | 1/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.54 |
| ▸ | CDK8 | P49336 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 4/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20501157 | 0.91 | SCN9A (0.57) | KDRSCN9ASCN4ASCN3ACNR1 | |
| SCHEMBL20501030 | 0.91 | SCN9A (0.61) | KDRSCN9ASCN4ASCN3ACDK8 | |
| SCHEMBL20501076 | 0.90 | SCN9A (0.61) | KDRSCN9ASCN4ASCN3ANPC1 | |
| SCHEMBL20500996 | 0.89 | SCN9A (0.53) | KDRSCN9ASCN4ASCN3ACDK8 | |
| SCHEMBL20501013 | 0.88 | CNR1 (0.61) | SCN9ASCN4ASCN3ACNR1 | |
| SCHEMBL20500999 | 0.88 | SCN4A (0.50) | KDRSCN9ASCN4ASCN3ANPC1 | |
| SCHEMBL20501054 | 0.87 | CNR1 (0.57) | KDRSCN9ASCN4ASCN3ANPC1 | |
| SCHEMBL20501115 | 0.87 | SCN9A (0.52) | KDRSCN9ASCN4ASCN3ANPC1 | |
| SCHEMBL20500990 | 0.87 | SCN9A (0.52) | KDRSCN9ASCN4ASCN3ACDK8 | |
| SCHEMBL20500943 | 0.87 | SCN9A (0.55) | KDRSCN9ASCN4ASCN3ACDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-01-06 | — | — | US | disclosed |
| CN-110740645-A | 2-aminoimidazole-phenyl derivatives for controlling microbial growth | 北卡罗莱纳州立大学 | 2020-01-31 | — | — | CN | disclosed |
| WO-2018169752-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11582970-B2 | 2-aminoimidazole-phenyl derivatives useful for controlling microbial growth | DDC, IL4I1, ING2 | KDR 2600/4885SCN9A 4811/4885SCN4A 4688/4885 |
| US-20220000118-A1 | 2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH | DDC, IL4I1, ING2 | KDR 2600/4885SCN9A 4811/4885SCN4A 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.