Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 10/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794226 | 0.93 | DNM1 (0.53) | KDM4EDNM1PAOXALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL793323 | 0.91 | DNM1 (0.52) | KDM4EDNM1PAOXKDM4AKDM4C | |
| Methylamine SCHEMBL28500749 | 0.89 | DNM1 (0.50) | KDM4EDNM1PAOXALDH1A1TSHR | |
| SCHEMBL1414877 | 0.83 | — | — | |
| SCHEMBL27503353 | 0.82 | DNM1 (0.53) | KDM4EDNM1PAOXALDH1A1TSHR | |
| SCHEMBL18339127 | 0.82 | SIGMAR1 (0.41) | DNM1KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL885320 | 0.82 | KDM4E (0.65) | KDM4EDNM1PAOXALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL17022764 | 0.81 | DNM1 (0.47) | KDM4EDNM1ALDH1A1 | |
| SCHEMBL20270807 | 0.81 | DNM1 (0.37) | KDM4EDNM1PAOX | |
| SCHEMBL16303439 | 0.80 | KDM4E (0.70) | KDM4EDNM1PAOXKDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609888-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | Metacrine, Inc. (US) | 2020-02-19 | — | — | EP | claimed |
| WO-2018170182-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | METACRINE, INC. (US) | 2018-09-20 | — | — | WO | claimed |
| WO-2023154818-A1 | MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS | MODERNATX, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023076605-A1 | LIPID AMINES | MODERNATX, INC. (US) | 2023-05-04 | — | — | WO | disclosed |